MTHFR Genetic Test

OPENSHOP PRODUCT DETAILS Live PDP hero embed product slug: taken from the page URL, /products/<slug> Select this block, open Settings, then choose Edit code.

OPENSHOP PRODUCT DETAILS Live PDP hero embed product slug: bioage Select this block, open Settings, then choose Edit code.

The Detail

Everything in the kit

Benefits

What your one-page MTHFR Report covers:

Your genotype at both positions tested Your report gives the genotype found at MTHFR (C677T) and at MTHFR (A1298C), with the result for each position, for example "No mutation detected" or "Heterozygous mutation detected".

An explanation of your results The report explains what your combination of genotypes means: how likely that configuration is in the general population, and how much your MTHFR enzymatic activity may be decreased below normal.

Where to learn more Your report links to MTHFR.IDLife.com, where you can learn more about the MTHFR gene.

Reviewed by the laboratory director Results are reviewed by Dr. Charles Sailey, Laboratory Director at Molecular Testing Labs.

The alleles tested and the reference range Your report's Test Details table gives the alleles tested, rs1801133 C>T (677C>T) and rs1801131 A>C (1298A>C), and the reference range they are read against, 677CC, 1298AA.

The published sources behind the interpretation Your report cites Circulation. 2005: 111(19): e289-83 and J Mol Med (Berl). 2001: 79(9): 522-528.

*These statements have not been evaluated by the Food and Drug Administration. IDLife products are not intended to diagnose, treat, cure or prevent any disease.

Product Details

In the box: IDLife MTHFR Testing Kit, a Return Envelope with Pre-paid Postage, MTHFR genetic testing performed by Molecular Testing Labs, and your Personal MTHFR Report
Positions tested: MTHFR C677T (rs1801133 C>T) and MTHFR A1298C (rs1801131 A>C)
Method: PCR with allele-specific probes and/or the amplification refractory mutation system (ARMS)
Report: Your Personal MTHFR Report, delivered by email
Results: About 3-4 weeks after the lab receives your swabs
Laboratory: Molecular Testing Labs™, a CLIA and CAP accredited laboratory
Item code: 05-0042

How to Use

Three steps take you from registering your kit to reading your report:

1 · Register your kit

Upon receiving your MTHFR Kit, make sure to register it following the instructions inside your kit.

2 · Collect and return your sample

Then, collect your DNA sample in the comfort of your own home and return it to the lab using the pre-paid envelope.

3 · Receive your report

After the lab receives your swabs, you'll receive an email notifying you. Then, you will receive your report in about 3-4 weeks via email.

This test was developed and its performance characteristics determined by Molecular Testing Labs. It has not been approved by the US Federal and Drug Administration (FDA). The FDA has determined that such clearance or approval is not necessary.

Discover Your MTHFR Gene

What is the MTHFR Genetic Test?

What you don’t know about your health could be keeping you from the results of your dreams.

While MTHFR may give you a double take at first glance, it actually refers to a particular gene in the body that is required for a metabolic process that repairs DNA, switches genes on and off, assists the body’s expulsion of toxic chemicals, and numerous other important functions. MTHFR is also essential to convert folic acid and folate – each a form of Vitamin B9 – into the biologically active form called L-Methylfolate (5-MTHF).

People that have a polymorphism, also known as a variant, on this gene at either the C677T or A1298C position have reduced function in these areas that can lead to certain health concerns. The MTHFR Test can identify for you any variants you may have on your MTHFR gene at either the C677T or A1298C position and provide a simple 1-page report that will allow you to put this information into action in your daily diet and lifestyle.

From Swab To Report

How the MTHFR Test Works

Discover your MTHFR gene to discover even more about your health! Here is the path from your kit to your report:

The Kit

IDLife MTHFR Testing Kit

Return Envelope with Pre-paid Postage included

We recommend you ship your kit back to Molecular within 60 days of receiving it, and immediately after collecting the specimen to avoid any chance of contamination to the swabs.

The Lab

Molecular Testing Labs™

CLIA and CAP accredited

MTHFR Genetic Testing is performed by Molecular Testing Labs™, a CLIA and CAP accredited, state-of-the-art, esoteric laboratory. The results provided are for informational purposes only, and not intended to diagnose, treat, cure or prevent any disease.

The Report

Your Personal MTHFR Report

Delivered by email

In about 3-4 weeks you will receive your MTHFR Report.

The Result

With this knowledge, you can adjust your diet and lifestyle, and in some cases your supplementation, to address this all-too-common issue, and get back to feeling your best with the peace of mind only knowledge can provide.

View MTHFR Facts

The Science of MTHFR: Problem & Solution

Why folic acid matters

For decades folic acid has been the first line of defense for folate deficiency and related health conditions, such as high homocysteine levels and neural tube defects. Any folic acid we ingest must be metabolized before it can be transported into cells, tissues and even across the blood-brain barrier for use.

The problem for people with MTHFR variants

Individuals with MTHFR variants have difficulty with the final metabolic step that converts folic acid to the active form L-Methylfolate (5-MTHF), which has been shown to lead to high levels of homocysteine in the blood and low levels of certain key vitamins, especially B12 and Folate (B9).

Why homocysteine levels matter

Homocysteine is an amino acid produced when proteins are broken down. High homocysteine levels, also called hyperhomocysteinemia, is usually asymptomatic by itself, but is almost always associated with a deficiency of Vitamin B12 or Folate.

Common signs of B12 or Folate deficiency

Though symptoms can vary from person to person, common signs of Vitamin B12 or Folate deficiencies include fatigue, tingling sensations in extremities, muscle weakness, confusion, forgetfulness, dizziness, and mood changes.

Homocysteine left unregulated

As for high homocysteine levels, if they are allowed to go unregulated, a person could be at an increased risk of developing a number of health issues like osteoporosis, atherosclerosis (buildup of fats and other substances in the arterial walls), thrombosis (blood clots in blood vessels), venous thrombosis (blood clots in the veins), coronary artery disease, stroke, dementia and Alzheimer’s disease.

2 positions

The test covers your MTHFR gene at either the C677T or A1298C position

50 States

The MTHFR Test is available to consumers in all 50 states

CLIA & CAP

Accreditations held by our partner laboratory, Molecular Testing Labs™

QUESTIONS

Frequently Asked Questions

How is the sample collected?

You will use a cotton swab provided by our partner laboratory to collect cheek cells from the inside of your mouth.

What’s the difference between the MTHFR Test and Genetic Test?

The MTHFR Test provides testing only on the C677T and A1298C genes and provides you a simple one-page report on whether you have variants on those genes. The Genetic Test provides testing on 39 different genes, INCLUDING your MTHFR C677T and A1298C genes, and gives you a 43 page report that goes into detail on how your body responds to diet and exercise based on your unique genetic profile.

How old do I have to be to get tested?

There is no age limit on our testing, though parental consent is needed to test anyone under the age of 18. IDLife requires that the parent or guardian sign the consent form of any person under the age of 18 and may ask for further verification as needed for authorization.

Do I have to pay for shipping back to the lab?

No. We will provide you with a pre-paid return shipping bag to send the sample back.

Are you going to sell my data?

IDLife partnered with Molecular because they are a HIPAA compliant and CAP-accredited laboratory committed to keeping all of your data private and secure. We will never sell your data and personal information to a 3rd party. If your data is ever used for further research, all identifying information will be stripped away so that it could never be linked back to you in the future. However, it is extremely rare that such a situation would happen. You have the right to opt out of any further use of your data.

Do you accept insurance?

No. We do not accept insurance for this type of testing.

What should I do if I have questions about my results?

We would love to answer your questions. Please call (972) 987-4430 or email info@idlife.com, and one of our Customer Advocates will be happy to assist you in getting your questions answered by our partner laboratory.

Pairs Well With

Everything in the kit

What is the MTHFR Genetic Test?

How the MTHFR Test Works

The Science of MTHFR: Problem & Solution

Frequently Asked Questions

You may also like